Guren has shown to be very mysterious, apparently preferring to keep to herself despite having a strong loyalty to Orochimaru. During her introduction, she quickly showed herself to be a remorseless and sadistic person. When told by Kabuto that several prisoners would be fighting to the death, she became ecstatic to hear there would be a slaughter. Guren is also shown to be vain by the fact that when she used her Crystal Release: Jade Crystal Mirror, she looked at herself and said, "Lovely, as always." She has also shown to be very proud. When Naruto offered to carry her, she was embarrassed because she felt it was shameful.