Pamela Isley was a brilliant but obsessive botanist who gained an immunity to toxins and turned to a life of crime, leading to confrontations with Batman. She had the same expertise with plant-based poisons and pheromones, along with a certain degree of control over plant life. Her weapon of choice was a wrist-mounted crossbow. It was in this series that Ivy first became friends and partners with Harley Quinn. While Poison Ivy often takes the role of a close friend or even a protective and familiar role towards Harley, there has also been some serious speculation (or perhaps wishful fantasizing) about a sexual nature to the affiliation.