The series follows the Thornberrys, as they travel the world in their "Commvee" (short for Communications Vehicle... basically an RV) looking for rare animals to film. Their youngest child, Eliza, is the main character. Thanks to an African shaman, Eliza has the power to speak to animals. She can speak to the family's pet chimpanzee, who is also her best friend. She travels the world with her family and usually helps animals solve their problems. The show currently airs on Nicktoonsters in the UK.
At the beginning of every episode, Eliza recites a monologue, which is then followed by the theme music. It states the basic premise of the show, and provides a brief back story so anyone new to the show would understand what's going on.